DNA For Dog Breeders
Carol Beuchat PhD
Institute of Canine Biology
Sign me up!
Types of DNA data
- parental verification
- low and high density genotyping
- whole genome sequencing
- mutation and association tests
- GWAS (genome-wide association study)
- SNP (single nucleotide polymorphism) & microsatellites (STR)
- understanding genotype data
- platforms (Illumina, Affymatrix, STRs)
- data quality
- assumptions for analyses
Getting the Data
- what data do you need?
- which test to use (Embark, MyDogDNA/Mars, UCDavis)?
Information Derived from DNA Data
- heterozygosity, genetic diversity
- inbreeding (identity by descent)
- shared homozygosity
- kinship coefficient
- runs of homozygosity
- population genetic structure
- principal components analysis (PCA)
- linkage disequilibrium
- DLA haplotypes
- lineage markers- Y chromosome, mtDNA (mitochondrial DNA)
- cluster analysis
- phylogenetic relationships
- ancestral breed composition
- evidence of admixture (cross with another breed)
Applications of data
- identification of mutations
- trait and disease association
- design of breeding strategies
- breeder tools (MyDogDNA, ICB, UC Davis)
How long? How much?
The course is approximately 10 weeks; fee is $125. After you register, you can sit in on the course again as many times as you want.
How much time will it take?
Generally there will be 3-5 hours of reading and homework exercises each week. You can work on the class schedule or at your own pace. There is no class meeting time - materials will be available to you 24/7 through the course website.
How will we meet?
The course is held entirely online. We will have a private Facebook group where we can discuss and ask questions. You can live anywhere in the world; all you need is an internet connection.
What do we need?
Just an internet connection!