HETEROZYGOSITY
(Donner et al 2018)
(Bannasch et al 2021)
I created these graphs from the data in the paper by Donner et al 2018, which includes more than 200 breeds of purebred dogs. The first graph (blue bars) represents >800,000 mixed breed dogs. You can use this graph to assess what "high" heterozygosity looks like for comparison with the purebreds.
The x-axis is the same on all of the graphs to make it easy to compare breeds (except the Lundehund, with heterozygosity too low to for the scale used for the rest of the breeds). The y-axis is always % of dogs, scaled appropriately for the size of the bars. The sample size is indicated under the breed name. For many of these breeds, there are dogs from multiple countries, so a graph does not represent a single population, but a breed that might have subpopulations around the world. See the Donner publication (link below) for details about the dogs and analyses.
The x-axis is the same on all of the graphs to make it easy to compare breeds (except the Lundehund, with heterozygosity too low to for the scale used for the rest of the breeds). The y-axis is always % of dogs, scaled appropriately for the size of the bars. The sample size is indicated under the breed name. For many of these breeds, there are dogs from multiple countries, so a graph does not represent a single population, but a breed that might have subpopulations around the world. See the Donner publication (link below) for details about the dogs and analyses.
| donner_et_al_2018_genetic_prevalence_and_clinical_relevance_of_canine_mendelian_disease_variants_in_over_one_million_dogs.pdf |
| donner_suppl_files.zip |
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