The Institute of Canine Biology
  • HOME
  • Blog
  • Breed Preservation
    • Breed Status
    • Breeding for the future >
      • BFF Breed Groups
    • The "Elevator Pitch"
    • What's in the Gene Pool?
    • The Pox of Popular Sires
    • What population genetics can tell us about a breed
    • What population genetics can tell you...Tollers & Heelers >
      • More details about the Toller study
    • How population size affects inbreeding
    • Finding the genes without DNA
    • Global Pedigree Project >
      • The Database
    • How to use kinship data
    • Using EBVs to breed better dogs >
      • EBV Examples
    • How to read a dendrogram
  • Projects
    • How To Interpret Breed Analyses
    • Afghan Hound
    • Belgian Tervuren >
      • Belgian Terv p2
      • Belgians- why population size matters
    • Bernese Mountain Dog
    • Boxer
    • Canaan Dog >
      • Canaan analyses
    • Cesky Terrier >
      • Cesky genetic history
    • Chinook
    • Curly-coated Retriever
    • Doberman
    • Entelbucher Mountain Dog
    • Flatcoat Retriever
    • French Bulldog
    • German Shorthair
    • Golden Retriever >
      • Golden Retriever Pedigree Charts
    • Irish Water Spaniel >
      • IWS (6 Nov 17)
    • Manchester Terrier
    • Mongolian Bankhar >
      • Research Updates
      • Bankhar 1
    • Norwegian Lundehund
    • Plummer Terrier
    • Otterhound
    • Portuguese Water Dog >
      • Portuguese Water Dog (pt 2)
    • Ridgeback
    • Schipperke
    • Standard Poodle >
      • The Problem With Poodles
      • 3poodle pedigree charts
      • 3Poodle Wycliff dogs
      • Poodle Genetics
    • Tibetan Mastiff
    • West Highland White Terrier
    • Whippet
    • Wirehaired Pointing Griffons
    • UK KC Graphs >
      • UK KC Breed Status
      • UK Groups
      • KC Gundogs
      • KC Hounds
      • KC Terriers >
        • Terriers (select breeds)
      • KC Pastoral
      • KC Toys
      • KC Working
      • KC Utility
      • Australian KC
    • Breed outcrossing programs
  • Courses
    • The Biology of Dogs
    • Basic Population Genetics for Dog Breeders
    • Managing Genetics for the Future >
      • Syllabus - Managing Genetics for the Future
    • DNA For Dog Breeders >
      • Syllabus - DNA for Dog Breeders
    • Genetics of Behavior & Performance >
      • Syllabus - Genetics Behavior & Performance
    • Understanding Hip & Elbow Dysplasia
    • Genetics for Preservation Breeders
    • Seminar - What's a Popular Sire?
    • FREE COURSES >
      • Quickie Genetics (Free!)
      • Heredity & Genetics (Free!)
      • Useful Genetics (Free!)
      • COI BootCamp (Free!) >
        • COI Bootcamp Graduates
  • Health Data
    • Genetic disorders by Breed
    • UK KC 2004 Survey
    • Bloat (Purdue Study)
    • Body Condition Score >
      • % Dysplastic vs BCS
    • Breed Comparions
    • Cancer
    • Cardiac
    • Cataracts
    • Caesareans
    • Deafness
    • Degenerative Myelopathy
    • Elbow Dysplasia
    • Epilepsy
    • Genetic Diversity
    • Genetic Diversity (MyDogDNA)
    • Hip Dysplasia >
      • Hip Dysplasia (Hou et al 2013)
    • Inbreeding Effects
    • Inbreeding (Gubbels)
    • Inbreeding (Dreger)
    • Lifespan
    • Litter size
    • Metabolic
    • mtDNA
    • Orthopedic
    • Mode of Inheritance
    • Patella Luxation
    • Thyroid
    • Portosystemic shunt
    • Purebred vs Mixed (UC Davis)
    • Purebred vs Mixed Breed (Bonnett)
    • Spay & Neuter Effects
    • Calboli et al 2008
    • Hodgman (1963)
    • Scott & Fuller (1965)
    • Stockard: Purebred crosses
    • Summers (2011)
  • Resources
    • Genetics Databases
    • Stud Books >
      • American Kennel Club stud books
      • Field Dog stud books
      • The Kennel Club (UK)
    • Learn
    • Videos about dog genetics
    • The Amazing Things Dogs Do! (videos) >
      • Livestock Management
      • Livestock guarding
      • Transportation, exploration, racing
      • Conservation & wildlife management
      • Detection Dogs
      • Medicine & Research
      • Entertainment
    • AKC/CHF Podcasts
    • Bookshelf
    • Read & Watch
  • About Us
    • Contact
    • Carol Beuchat, PhD
    • Robert Lacy, PhD
    • Peer Berg, PhD
    • Thomas Famula, PhD
    • Heather Huson, PhD
    • Iwona Glazewska, PhD
    • Will Ludington, PhD
    • Claudia Melis, PhD
    • Jennifer Mickelberg, PhD
    • Torsten Nygaard Kristensen, PhD
    • Thomas Mitchell
    • Pieter Oliehoek, PhD
    • CA Sharp
    • Rory Todhunter, PhD
  • ICB Breeder Tool
  • DNA For Dog Breeders
  • Belgian Sheepdogs
  • New Page

Reliability of DNA tests for inherited diseases in dogs

12/21/2015

 
By Carol Beuchat PhD

As the list of available DNA tests for genetic disorders grows ever longer and the number of laboratories offering them multiply, the dog owner is left to evaluate the reliability of both the test and the tester, something that is beyond the ability of the lay person and perhaps even the veterinarian. So it is nice to see the publication of a report that does just that coming out of a Master's thesis by Maaike Fennema from the veterinary school at Utrecht University in The Netherlands.

I think you will find this to be a valuable reference.

Abstract
The change of the ‘’Wet Dieren’’, by the Dutch government, requires the breeders to screen their parental dogs for inherited diseases. Since the breeders and the veterinarians have to apply the DNA tests and they do not have all the knowledge about these test, this study aims to make a  list including all the available DNA test on the Dutch market. To know if the offered test are substantiated, they will be evaluated using a set of criteria developed during this project. First, all the DNA test were gathered from the four biggest laboratories for the Dutch market, Laboklin, VetGen, Van Haeringen and Optigen. This resulted in a list containing 120 different diseases. In this article the focus was on cardiovascular and blood diseases, metabolic and immune problems and eye disorders. If the DNA test fulfil the criteria they will be published on the website of ‘Expertisecentrum Genetica Gezelschapsdieren’. The most important criterion was that there was a peer reviewed article available about the mutation they tested on. So for all the DNA tests, articles were searched and reviewed. The research resulted in a list of in total 11 cardiovascular and blood diseases, 23 metabolic and immune problems and 27 eye disorders.

You can access the document as a pdf that includes the appendices here.​
fennema_2015_reliability_of_dna_tests_for_inherited_diseases.pdf
File Size: 997 kb
File Type: pdf
Download File




Check out
ICB's online courses
​

*******************

Coming up NEXT -
​
Understanding Hip & Elbow Dysplasia

Next class starts
​
4 January 2016



Managing Genetics for the Future
Next class starts
18 January 2016
​

​Sign up now!



***************************************

Visit our Facebook Groups

ICB Institute of Canine Biology
...the latest canine news and research

ICB Breeding for the Future
...the science of dog breeding
​

Comments are closed.

    RSS Feed

    Archives

    January 2020
    October 2017
    August 2017
    May 2017
    April 2017
    March 2017
    February 2017
    January 2017
    December 2016
    November 2016
    September 2016
    August 2016
    July 2016
    June 2016
    April 2016
    March 2016
    February 2016
    January 2016
    December 2015
    November 2015
    October 2015
    September 2015
    August 2015
    July 2015
    June 2015
    May 2015
    April 2015
    March 2015
    January 2015
    December 2014
    November 2014
    October 2014
    September 2014
    August 2014
    July 2014
    June 2014
    May 2014
    February 2014
    December 2013
    October 2013
    September 2013
    July 2013
    March 2013
    July 2012
    April 2012

    Categories

    All
    Behavior
    Border Collie
    Herding

Blog

News


About Us

Contact Us








Copyright © 2012-2017 Institute of Canine Biology
Picture
Picture
✕