SYLLABUS
DNA for Dog Breeders
Module 1 - Introduction to the course
Module 2 - Will DNA tests eliminate genetic disorders in dogs?
Module 3 - DNA Nuts 'n Bolts
Module 4 - How does DNA work?
Module 5 - Types of mutations
Module 6 - Genetics of traits and diseases
Module 7 - Types of DNA markers
Module 8 - DNA analysis
Module 9 - Identifying genes for traits and diseases
Module 10 - DNA testing
Module 11 - Choosing the right tests
Module 121 - Who does DNA testing?
Module 13 - Using DNA information for traits & disorders
Module 14 - Using individual genomic data
Module 15 - Using population genomic data
Module 16 - Breed composition
Module 17 - Breeding for traits and genetic health
Module 18 - Population genetic structure
Module 19 - Breeder tools
Module 20 - Software and other tools
- Welcome to "DNA for Dog Breeders"
- Why use DNA analysis?
- What the course will cover
- Who is the course for?
- Course policies
Module 2 - Will DNA tests eliminate genetic disorders in dogs?
- Can we test our way to healthy dogs?
Module 3 - DNA Nuts 'n Bolts
- What is DNA?
- Structure of DNA
- Types of DNA
- What is a chromosome?
Module 4 - How does DNA work?
- DNA and genes
- Genes and alleles
- How do genes make proteins?
Module 5 - Types of mutations
- Missense mutation
- Nonsense mutation
- Deletion
- Insertion
- Duplication
- Frame shift
- Copy number variation
- Repeat expansion
Module 6 - Genetics of traits and diseases
- Genotype determines phenotype
- Monogenic traits
- Polygenic traits
- Complex traits
Module 7 - Types of DNA markers
- What are markers?
- Microsatellites
- SNPs
- DLA testing
- Haplotypes and haplogroups
- Other types of markers
Module 8 - DNA analysis
- Whole genome sequencing
- "Next generation" sequencing
Module 9 - Identifying genes for traits and diseases
- Finding genes
- GWAS
- Association testing
Module 10 - DNA testing
- How reliable are DNA tests?
- Single mutation tests
- Association tests
Module 11 - Choosing the right tests
- What information do you need?
- How will the information be used?
- Other considerations (e.g., compatibility, obselescence)
- What is most cost effective?
Module 121 - Who does DNA testing?
- Single trait testing
- Microsatellite-based genomics
- SNP-based genomics
Module 13 - Using DNA information for traits & disorders
- Understanding your report
- Assumptions and limitations of tests
Module 14 - Using individual genomic data
- Quantifying inbreeding
- Verifying parentage
- Visualizing DNA on the chromosome
Module 15 - Using population genomic data
- Determining population genetic diversity
- Determining relatedness and kinship
- Determining effective population size
Module 16 - Breed composition
- Breed verification and purity
- Determining breed composition
- Historical admixture
Module 17 - Breeding for traits and genetic health
- Using DNA to improve genetic diversity
- Genomic selection
- Genetics of quantitative traits
- Predicting litter phenotype
Module 18 - Population genetic structure
- Identifying subpopulations
- Determining genetic distance
Module 19 - Breeder tools
- UC Davis Genetic Diversity Test
- MyDogDNA Health Index
- ICB Breeder Tool
- Choosing the right tool to use
Module 20 - Software and other tools
